TY - JOUR ID - 113603 TI - Synthesis of a Macroporous Glass-Ceramic Scaffold Containing Fluorapatite Crystalline Phase for Bone Substitutes JO - Advanced Ceramics Progress JA - ACP LA - en SN - 2423-7477 AU - Rezvani, M. AU - Alahgholiyan, E. AU - Roshangar, L. AD - Department of Materials Engineering, Faculty of Mechanical Engineering, University of Tabriz, Tabriz, Iran AD - Histology and Embryology Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran Y1 - 2020 PY - 2020 VL - 6 IS - 3 SP - 47 EP - 54 KW - Glass-ceramic KW - Fluorapatite KW - Macroporous KW - Porogen DO - 10.30501/acp.2020.113603 N2 - Bioactive glass-ceramics play an important role in bone tissue regeneration. In the present research, the crystallization of glasses and scaffold fabrication were investigated. After choosing the appropriate composition in the SiO2-CaO-Na2O-p 2O5 system, raw materials were melted at 1400  and then, quenched in water. Subsequently, the crystallization of synthesized glass samples was studied. Fourier Transfer infrared (FT-IR) spectroscopy was carried out to study the structural changes of the samples. XRD patterns showed that fluorapatite Ca10(PO4)6(O,F2) was the only precipitated crystalline phase. The template synthesis method was applied for the fabrication of the scaffold and starch as a porogen material. The optimized scaffold structure was chosen with the appropriate size of pores, interconnectivity, and strength behavior through investigating the porosity, SEM images, and mechanical properties. ICP, SEM, and EDX analyses were used to determine the in vitro bioactivity of the samples after immersion for 14 days in SBF. UR - https://www.acerp.ir/article_113603.html L1 - https://www.acerp.ir/article_113603_1e6a0d3e620dc71da48de0104f9bd842.pdf ER -