TY - JOUR ID - 161855 TI - Investigation of the Coating Methods and Types of Coatings Containing Hydroxyapatite for Applications in Tissue Engineering JO - Advanced Ceramics Progress JA - ACP LA - en SN - 2423-7477 AU - Doudkanlouy Milan, Behnam AU - Mohammadzadeh, Hurieh AU - Jafari, Robabeh AU - Soltani, Mohammad AD - MS Student, Department of Materials Engineering, Faculty of Engineering, Urmia University, Urmia, West Azerbaijan, Iran AD - Assistant Professor, Department of Materials Engineering, Faculty of Engineering, Urmia University, Urmia, West Azerbaijan, Iran AD - PhD Candidate, Department of Materials Engineering, Faculty of Engineering, Tarbiat Modares Universirty, Tehran, Tehran, Iran Y1 - 2022 PY - 2022 VL - 8 IS - 4 SP - 32 EP - 41 KW - Hydroxyapatite KW - coating KW - metal substrates KW - Osteoinduction KW - Tissue engineering DO - 10.30501/acp.2022.365116.1108 N2 - In recent years, application of Hydroxyapatite (HA) as the coating on metal substrates for biological stabilization of implants, stimulation of bone growth around the implant, and optimization of recovery time has attracted the attention of many researchers around the world. In this regard, the current study presented a review of HA and its composite coatings for tissue engineering applications. HA is one of the bioceramics that has been an interesting subject of research in recent years owing to its in-vitro bioactivity, osteoinduction, and osteoconduction properties. According to the previous reports, coated implants were performed successfully to achieve high corrosion resistance, bone growth and regeneration, and reduction of corrosion current density. The current research presented a review of the previous research works on the coating mechanism, physico-mechanical, in-vitro bioactivity, and biocompatibility properties of HA and its composite coatings on substrates. The obtained results revealed that HA and its composites had a synergistic effect on the metal substrates in terms of improving corrosion resistance, providing biocompatibility, direct bonding to tissue, accelerating treatment, and reducing costs imposed on the health care sector. UR - https://www.acerp.ir/article_161855.html L1 - https://www.acerp.ir/article_161855_4458a1f80d3548853d271e522c7d08ed.pdf ER -